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Table 1 Overview of the definitions of surgical site infections

From: Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple resection (SPARROW): a study protocol for a multicentre, open-label, randomised controlled trial

Type surgical site infection (SSI)

Description

Superficial incisional SSI

Wound infection defined according to the CDC definition [17]

Organ/space SSI (OSI)

A deep SSI involving any part of the abdomen (e.g. organs and/or spaces) other than the surgical incision [17]

Isolated OSI

Isolated (non-pancreatic fistula) OSI: absence of concurrent anastomotic leak (pancreatojejunostomy, defined as postoperative pancreatic fistula (POPF), hepaticojejunostomy or gastrojejunostomy)

Non-isolated OSI

Not-isolated OSI: concurrent anastomotic leak (at time of OSI diagnosis)

Clinically relevant OSI (primary outcome)

An isolated or non-isolated OSI is clinically relevant in case of:

- Requirement of a radiological, endoscopic or surgical intervention, or therapeutic antibiotics for an episode of sepsis (defined as two or more SIRS criteria)

and

- Organisms isolated from an aseptically obtained culture